• No-Tox | Peptide Serum
  • No-Tox | Peptide Serum
  • No-Tox | Peptide Serum
  • No-Tox | Peptide Serum
  • No-Tox | Peptide Serum
  • No-Tox | Peptide Serum
  • No-Tox | Peptide Serum
  • No-Tox | Peptide Serum
  • No-Tox | Peptide Serum
  • No-Tox | Peptide Serum
MyDermaDream

No-Tox | Peptide Serum

$80.00
$80.00
Sale Sold out

FREE SHIPPING Over $100 | 90 Days Guarantee

Expected delivery in 3-5 business days

Powered by a clinically studied blend of peptides and antioxidants, every drop works to visibly smooth the appearance of fine lines and wrinkles. For skin that looks firmer, more lifted, and more radiant with every use.

Add On
Lift & Glow Guasha Pro
MyDermaDream
Lift & Glow Guasha Pro
From $59.00
From $59.00 -25%
$79.00
MDD Lifting & Skin
Firming Moisturizer
MyDermaDream
MDD Lifting & Skin
Firming Moisturizer
From $67.00
From $67.00 -66%
$201.00

Visibly firmer, smoother, more lifted-looking skin — no appointments necessary.

Five clinically studied ingredients, chosen for their visible impact on fine lines, wrinkles and firmness. With consistent daily use, No-Tox may help:

  • Reduce the appearance of fine lines and wrinkles

  • Improve the look of skin firmness and elasticity

  • Restore a plumper, more hydrated appearance

  • Support a more even, brighter-looking skin tone

Five hero ingredients

  • Matrixyl® — studied for the appearance of wrinkles and skin texture

  • Argireline® — studied for the appearance of expression lines

  • Matrixyl® Synthe-6™ — studied for smoother, more youthful-looking skin

  • Stay-C® — stable Vitamin C; helps brighten and defend against environmental stressors

  • Hyaluronic Acid — binds moisture to plump the look of skin

Also features Olive Leaf, Aloe Vera, Shea Butter, Chamomile and Green Tea.

How to use — Morning and evening: cleanse, massage a small amount onto face and neck, let it absorb, then moisturize.

90-Day Satisfaction Promise. If it's not right for you, tell us within 90 days and we'll send you a different formula, free.

Individual results vary.

With consistent use, No-Tox may help:

  • Soften the look of fine lines and expression lines
  • Firm and lift the look of your skin
  • Restore a plumper, more hydrated appearance
  • Support a brighter, more even-looking skin tone

Lightweight and fast-absorbing — layers well under moisturizer and makeup.

  • Argireline® Peptide | The Expression Line Smoother
  • Matrixyl® | The Gold Standard in Visible Wrinkle Care
  • Matrixyl® Synthe-6™ | The Advanced Peptide Complex
  • Hyaluronic Acid | The Hydration & Plumping Essential
  • Stay-C® Vitamin C | The Skin Brightening Defender
  • Green Tea | The Environmental Aging Shield
  • Arginine | The Skin Resilience Booster

✓ You're noticing the appearance of sagging, wrinkles, or dullness

✓ You're ready for visible, consistent skin improvement

✓ You want a non-invasive routine you can do at home, on your schedule

✓ You're looking for a serum backed by clinically studied ingredients

Lifting & Firming Skin Care

Using our Youthful Five ingredient blend.

Real Results.
Real Self-Care.

Every product we make is designed to help you fall in love with your skin again. From contouring tools to targeted serums, we bring pro-level skincare home.

.
Backed by science, powered by expert guidance
.
Designed for all skin types—including sensitive & aging skin
.
Turns your routine into a ritual of self-care
.
Trusted by 250,000+ customers worldwide

“Derma Dream products are wonderful. I can’t wait to do my facial routine everyday. The company is great. They check in on me every couple weeks to see how I’m doing. Maica is amazing and very helpful. Thanks for being there for me on this journey.”

– Marjorie G.

"I've never been the most hydrated person—so I didn’t even know my skin could glow like this. Just one mask a week has made my skin feel soft, radiant, and evened out my fine lines and tone!"

– Sue, 42

How No-Tox Works

The Formula

This peptide-powered serum combines exosomes, collagen-supporting ingredients, and antioxidants to visibly improve the look of skin over time. With consistent use, skin appears smoother, firmer, and more radiant.

What You'll Notice

Every drop works to visibly reduce the appearance of fine lines, improve skin's look of firmness, and even skin tone. With daily use, skin looks visibly plumper and more lifted, no appointments necessary.

Shop Now

Argireline® Peptide

The leading peptide in wrinkle prevention, this powerful ingredient relaxes micro-tension in facial muscles—preventing deep expression lines from forming while smoothing existing creases.

Matrixyl®

A collagen-boosting powerhouse, Matrixyl® doubles collagen production, visibly plumping deep wrinkles and rebuilding ffskin’s density

Matrixyl® Synthe-6™

An advanced form of Matrixyl®, this peptide restructures the skin from within, improving volume and support while targeting deep-set wrinkles.

Stay-C® Vitamin C

This potent, stabilized Vitamin C fights oxidative stress while boosting collagen and fading dark spots, revealing a smoother, more radiant complexion.

Hyaluronic Acid

Known as the moisture magnet, Hyaluronic Acid retains up to 1,000x its weight in water, instantly plumping and smoothing fine lines.

Green Tea

Packed with powerful polyphenols, Green Tea protects against environmental aging factors, preventing collagen degradation and UV-induced wrinkles.

  • 90 Day Satisfaction Guarantee
  • Free Shipping On Orders Over $100
  • Visibly Firmer, More Lifted-Looking Skin
  • Subscribe & Save
  • Free Expert Skin Consultations Included

DermaDream vs
Spa Treatments

Visible, age-defying results—without the in-clinic cost.

Why pay thousands for treatments you can own?
Invest Once. Glow for life.

Science Backed Skin Care Treatments At Home

Traditional Med Spa

Fillers, Needles, Surgery (In Clinic)

World-Class Results

Formulated with clinically studied ingredients, designed to deliver visible results

Depends on the spa & treatment provider´s previous experience

Experience Compounding Results

Unlimited treatments, compounding results

Less frequent treatments, lose progress between each visit or pay $ thousands

Non-Invasive Pain-Free

Non-invasive, pain-free, no downtime

Needles, lasers & surgeries with real risks & long recoveries.

Ongoing 1:1 Support

Expert bi-weekly skin consults& 24/7 support.

In-and-out, just another client, no support beyond treatment

Beauty Backed by Data

5000+ customer transformations + log your own results in real-time in Derma Dream App

Hope for results, no trackingor follow-up

Rewarding Your Journey

Earn rewards for investing in you.

Pay more,get nothing extra.

Cost

Invest once, good for years

Continued spend, hassle of travel

Feminine Wellness Focus

Thriving Feminine Wellness Community with Masterclasses & Info Content

No support outside of appointment

“My Derma Dream as well as the customer service has really been top notch! I am very impressed by the device, the results on my skin and the customer service.”

– Yvonne A.

“Flora went above and beyond to take care and help with the perfect routine and care and Flora had amazing knowledge about the products. I love their skincare.”

– Kristina C.

“I thought my best skin was behind me—but  Derma Dream helped me unlock a glow and smoothness I never thought I’d see again.”

– Maria., 42, proving beauty blossoms at all ages.
Before
After

“I was this close to booking a spa appointment when my friend said, ‘Try No-Tox first.’

I was skeptical, but now?

My skin feels fuller, bouncier—actually smoother. I’m obsessed.”

Emma Suazo, 42

Frequently Asked Questions

Your skincare questions, answered—because confidence starts with knowing. 💫

Results vary by skin type and consistency of use. Most customers begin to notice visible improvements in skin texture and radiance within 2–4 weeks of daily use, with more significant changes in the appearance of fine lines and firmness typically visible at 6–8 weeks.

For best results, use morning and evening as part of a consistent skincare routine.

At My Derma Dream, our dedication to your skin's well-being is reflected in the thoughtful selection of premium ingredients we use. We believe in transparency — so you can fully understand what you're applying to your skin and why each ingredient earned its place in the formula.

  • Aqua (Water): The foundation of our formula, ensuring optimal delivery of active ingredients.
  • Aloe Barbadensis (Aloe Vera) Leaf Juice: Known for its soothing and moisturizing properties, aloe is a cornerstone of skin comfort and hydration.
  • Isopropyl Palmitate: A lightweight emollient that softens and smooths skin without leaving a greasy residue.
  • Sodium Ascorbyl Phosphate (Stay-C®): A stable, effective form of Vitamin C that visibly brightens skin tone and helps defend against environmental stressors.
  • Sodium Hyaluronate (Hyaluronic Acid): A moisture-binding ingredient that visibly plumps skin with hydration, reducing the appearance of fine lines and wrinkles.
  • Palmitoyl Pentapeptide-4 (Matrixyl®): A clinically studied peptide complex that visibly reduces the appearance of wrinkles and improves skin texture over time.
  • Hydroxypropyl Cyclodextrin and Palmitoyl Tripeptide-38 (Matrixyl® Synthe-6™): Helps visibly smooth the look of wrinkles for a more youthful-looking complexion.
  • Acetyl Hexapeptide-8 (Argireline®): Helps visibly soften the appearance of expression lines for a smoother-looking complexion.
  • Butyrospermum Parkii (Shea Butter): Provides deep moisturization, softens skin, and conditions with rich, nurturing care for a luxuriously smooth feel.
  • Matricaria Recutita (Chamomile) Flower Extract: Known for its soothing and calming properties, ideal for reducing the appearance of skin irritation and promoting a comfortable skin surface.
  • Camellia Sinensis (Green Tea) Leaf Extract: An antioxidant-rich extract that helps protect against the visible effects of environmental stressors.
  • Olea Europaea (Olive) Leaf Extract: Offers hydrating properties that promote a supple, firm-looking skin texture and improved tone.
  • Carbomer: A gelling agent that ensures a smooth texture for easy, even application.
  • Arginine: An amino acid that supports the look of healthy, resilient skin and a visibly radiant complexion.
  • Phenoxyethanol and Ethylhexylglycerin: Preservatives that keep our formula fresh and stable, ensuring consistent quality with every use.

By choosing No-Tox Serum, you're investing in a thoughtfully formulated blend of clinically studied ingredients designed to visibly improve the look of your skin over time.

No-Tox is formulated without added fragrance. It has a neutral scent, allowing it to be suitable for those with fragrance sensitivities. However, please note that it may have a slight natural scent due to the ingredients used, but this is typically subtle and dissipates quickly after applicati

Our serum is formulated with clinically studied ingredients that work together to visibly address the appearance of fine lines, wrinkles, and uneven skin texture. With consistent use, skin looks visibly smoother, more hydrated, and more radiant over time.

Yes, Notox is formulated to be suitable for most skin types, including dry, oily, combination, and normal skin. It is designed to address common skin concerns such as wrinkles, fine lines, dullness, and uneven skin tone. However, if you have specific skin conditions or sensitivities, it's always advisable to consult with a dermatologist before incorporating any new skincare product into your routine.

It's easy! Apply your No-Tox serum after cleansing and before moisturizing. A few drops in the morning and evening can pave the way for smoother, more resilient skin.

For best results, it is recommended to use No-Tox twice daily, in the morning and evening, as part of your skincare routine.

Results vary by skin type and consistency of use. Some customers notice visible improvements in skin texture and radiance within 7–14 days. For best results, we recommend consistent daily use for at least 30 days. With continued use, skin typically appears visibly firmer, more even-toned, and more radiant.

No-Tox is formulated without added fragrance and is designed to be gentle on most skin types, including sensitive skin. As with any new skincare product, we recommend patch testing before first use. If irritation occurs, discontinue use and consult a dermatologist.

Yes — No-Tox fits easily into your existing skincare routine. For best results, apply after cleansing and toning, and before moisturizing. Allow the serum to fully absorb before layering additional products such as moisturizer or sunscreen.

Yes, No-Tox can be used as a primer before applying makeup. It absorbs quickly into the skin, leaving a smooth and hydrated canvas for makeup application. Allow the serum to fully absorb before applying any makeup products for optimal results.

The longevity of a bottle of No-Tox depends on individual usage and the size of the bottle. As a general guideline, a standard-sized bottle should last approximately 1 to 2 months when used as directed. However, this can vary based on the amount of serum applied and the frequency of use.

New Products

Explore our latest skincare innovations for radiant skin.
(35 reviews)

MyDermaDream

Niacinamide Activator Serum

$20.00
$20.00
(27 reviews)

MyDermaDream

No-Tox | Peptide Serum

$80.00
$80.00
(No reviews)

MyDermaDream

MyoGlow LED Skin Lifting

From $79.00
From $79.00 -20%
$99.00
(19 reviews)

MyDermaDream

Glide & Glow Ultra-Creamy Plumping Serum

From $90.00
From $90.00 -66%
$270.00
(17 reviews)

MyDermaDream

MDD Lifting & Skin
Firming Moisturizer

From $67.00
From $67.00 -66%
$201.00
(No reviews)

MyDermaDream

Lift & Glow Guasha Pro

From $59.00
From $59.00 -25%
$79.00
(No reviews)

MyDermaDream

VisaSculpt | Microcurrent Facial Device

From $149.00
From $149.00 -34%
$229.00
  • 5 stars: 25 (93%)
  • 4 stars: 2 (7%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
S
Stephanie S.
Stephanie

Makes my lines not so big in my face. Not greasy but feels good

H
Hong C.
Excellent Customer Service

I bought a MyoGlow and a few bottles of serum came with it. I was not sure how to use those products. I called Customer service, and Chennie explained to me exactly what I needed to know. She also messaged me the information. I am very satisfied with the customer service at My Derma Dream.

J
Jennifer T.
Feels Good

I'm a sucker for serums these days because I really want the extra moisture and (fine) wrinkle care. Unfortunately, I also have very sensitive skin that is prone to breakouts. I've been using this serum for about 3 weeks - not long enough to for sure say it works, but definitely long enough to say that I've had no negative reactions. Even though it has vitamin C, which I'm normally very reactive to leading to red, irritated looking skin, my skin has not had any issues. It is lightweight, but not watery and soaks into the skin very quickly. It does not pill under my make up (either primer/BB tint or a powder foundation). I do feel moisturized but not oily.

N
NaughtiLiterati
Lovely face serum.

It is very moisturizing and I like the light fragrance. My skin feels so soft and supple when I put it on. I like to apply after toner and just a tad before I head out for the day and a little dab at night before bed!

R
Rosalye G.
Superior Customer Service

Maria D was my consultant from the get go and she had so much patience with me but even though I was very rdluctant to purchaae tbe recommended creams and lotions I am just super happy that I decidef to go ahead and order those crdams. Long story short Maria D was vedy proffesioal and has a lot of knowledge of the products she gave me the cinfidense I needed. I love my Maria D

Hi Rosalye,

Thank you so much for sharing your experience! 🌟 We're thrilled to hear how happy you are with your decision and the results. Maria D is truly amazing, and we're lucky to have her on our team. Your kind words about her patience, professionalism, and product knowledge mean a lot. We'll be sure to pass this along to her—she'll be so delighted to hear how much she helped you! 💖

R
Rebecca Q.
John has great customer service abilities!

John has been a huge help directing me on a regimen I should do to get the best results with the products I purchased. He even texted me a step by step process so I can go back and refresh my memory when needed. He worked with me to get a good deal and took care of getting me a new LED mask to take place of the first I that didn’t work. Thank you John for the great customer service!

Hi Rebecca,

Thank you so much for sharing your experience! 🌟 We're thrilled to hear how helpful John has been in guiding you through your regimen and ensuring you have everything you need for the best results. His dedication to providing step-by-step support and resolving issues like replacing your LED mask truly reflects his commitment to excellent customer service. We'll be sure to share your kind words with him—he’ll be so pleased to know he made a difference. Thank you for choosing My Derma Dream! 💖

D
Dorothy A.
An easier way for beauty

Well, I was asking for a
Refund for the Derma dream kit, due to the fact that when I ordered it I didn’t realize that I would be needing to apply the serum and use the Derma dream twice daily as I am disabled and live in chronic pain and only have a limited income on permanent disability which does not allow me to afford the serum’s on a regular basis, so instead of a refund they offered me a store credit of $200 too purchase a Derma glow mask that requires little effort to use and I can still have a very easy beauty routine. They were very understanding and helpful of my situation.

A
All P.A.t.T.
Too Soon to Say

I ordered this bottle of My Derma Dream No-Tox face serums for anti aging after looking in the mirror.

Some people like the way their hair looks when it starts to turn gray. Some people like the way a salt and pepper beard looks. I don't know anyone, though, who likes wrinkles. I thought I would give this product a shot.

These face serum follows the adage that "a little goes a long way." It takes very little to create a thin layer of serum on your face. To obtain the best results, though, you need to cover it with moisturizer. The serum caused me no irritation or allergic reaction. It has a barely perceptible odor.

Does it work to reduce wrinkles? Well, I've only been using it for a week and can't honestly say that I see any difference. Even if I did notice a slight reduction, I'm not sure that I would continue to use this product based on the cost.

K
Kathryn V.
I am so happy with your products !!!

I love the brushes and it makes it a breeze to apply! Also feels great on my skin and looks natural !! Quiet an easy. I’m nit a makeup person , but I don’t want to leave home without it on ! Looks great !!

Thank you for sharing your experience! 😊 We're so happy to hear that you love the product and how easy it makes applications. It's wonderful to know it feels great on your skin and gives a natural, flawless look! 💖

Your feedback means so much to us—thank you for being part of our community!

If you ever need anything, we're here for you. 😊

M
MsMiddleofMinnesota
Just a few drops.

Comes with a dropper. Very thin consistency that absorbs quickly. No scent.

D
Dee
I was assisted today by April

I was assisted today by April, and she was a pleasure to speak to. She helped explain everything to me and took the time to make sure that she really could understand what my skin concerns were. She also was patient in explaining to me the products that seemed best for my skin needs. I’m excited and can’t wait to receive my product in the mail !

M
Marjorie G.
My Derma Dream products are wonderful

My Derma Dream products are wonderful. I can’t wait to do my facial routine everyday. The company is great. They check in on me every couple weeks to see how I’m doing. Maica is amazing and very helpful. Thanks for being there for me on this journey.

C
Cynthia K.
Derma Dream is a skin care company that promises and delivers fantastic results!

I love this product and know it is making a difference! Jerika was very helpful answering my plethora of questions. She also sent me a step by step personalized regimen for optimal results, which I truly appreciated!

L
Lois T.
An amazing company and very trustworthy

I received a msg today from Sella from Derma Dream asking how I’m doing with my devices and serum.
I explained I love the devices I have also the serums are great, my face now has worked for my face , brighter, healthier. The only thing I’m working on now is my upper lip wrinkles.

Selle spent a good chunk of time to discuss my lip issue. We were figuring out which device would work for my issues.
They also send a new bottle of serum free if you’re running low.

I myself don’t think they should be responsible to give me a free one as I’m an adult and should know when to reorder ( for me)

I highly recommend My Derma Dream! They truly go above and beyond and don’t make you feel bad for askingThey truly work to fix whatever issue you have

L
Lillian B.
Jenny is amazing!! I Ordered my new products.

I spoke to Jenny today, and she was amazing! A great pleasure! She was so nice, sweet, & patient in answering all my questions, and very knowledgeable. Jenny provided me with much information about each product, and in guiding me through my skincare routine. She outlined everything step by step on what I need to do in order to obtain the maximum results for my skin type for what I want to achieve. She told me I can call her direct at any time if I have any questions or need any clarifications. It’s like having a beauty expert at your fingertips. I can’t wait to get my products; follow her instructions; and to see my results. Jenny was awesome! I will keep her posted with my new skincare regime and progress. Thank you Jenny.

B
B
Serum Lightweight

I highly recommend this. It does what it says. I use it with the massager and my skin feels and looks wonderful.

J
Jennene
Agent Kimberly

The agent, Kimberly was very nice, informative and helpful. She stated she would call periodically to check on my progress with product and skin regimen, that made me feel so comforted. I am looking forward to speaking with her again.

I
Irene
Donna's support

Donna has checked on me after I purchased My Derma to explain careful and thoroughly the steps to use my Derma. She is kind and knowledgeble.
She also respects my timmings and preferences and I strongly appreciate that she is not pushing me to buy more things. To have her on my side is a great support and encourages me to be thorough with my Derma experience. I haven't tried the results yet but I am excited to test the results
Thank you Donna for your kind service

2
206
Really nice

I have Botox all over my face so I’m hoping by using this I can extend the life of the tox so I don’t have to go to the spa quite as often! It’s smooth and silky and absorbs quickly into my skin. It’s non irritating to me.

S
Sonia T.
Really good serum

I definitely love this serum, I did notice a difference when using it with my Gua sha Pro.. it’s a winner

B
Binu A.
Excellent Customer Service

Customer service is too good.I asked for Talha .He attended the call.He was too good.Very much approachable.Always present in a proffessional way and with nice attitude and friendly too.He is a valuable asset in your dream dream.team.Good luck to him.

I love the Glide and glow serum ..It's the best.I did subscribe this serum.

W
Windy
I’m a DERMA dream customer love the personal consultant Judy

I’m a DERMA dream customer, it’s too early for me to say I’ve seen results. I can say I enjoy the products and how the light therapy, warmth and vibration makes my face and neck feel. I’ll give more feedback as results unfold. I do want to give a special thank you to Judy my personal consultant. She’s a true advocate interested in my needs & how she could help make things better.
I explained a few hiccups I had with original order she’s making arrangements to fix them. She wasn’t pushy on the products really listened. She was fantastic, If all goes with fixing my issues I’ll be a DERMA DREAM dream girl always. Thank you Judy for your belief in the products, listening to my concerns and your guidance. You’re a lifesaver, I appreciate everything and look forward to working with you. ( GREAT CUSTOMER SERVICE)

K
Kay T.
Great facial consultant

Great facial consultant, Jerome helped me to get the correct products I needed. He also emailed me a facial regime to follow using them. He took the time to answer my questions.I haven't gotten the products yet however I always do my research beforehand. That is why I choose Derma dream. He said I could call anytime. He is going to check on me in two weeks.

g
glam.beauty.chic
Love this! Botox effects!

It’s very hydrating, my skin feels and looks more plump because of all the collagen effects it has! Therefore, botox is not needed since this gives Botox effects! Such an amazing quality for a great price!

K
Kristina C.
Flora went above and beyond to take…

Flora went above and beyond to take care and help with the perfect routine and care and also Flora had amazing knowledge about the products. I love their skincare

G
Gail S.
My girl was wonderful

My girl was wonderful, she text me back-and-forth with questions and then we spoke on the phone and she was able to give me my daily routine which films to use when to use them and what color lights to use. She did expressed that the silk skin serum would be great for my neck at the time I cannot afford that but well in the future, again she was wonderful and I appreciate it.

Thank you
Gail Seaman

A
Alma C.
The texture of the product is incredibly light and absorb quickly into the skin, making it perfec...

Review for Michelle Ann: MyDerma Dream Experience. I wanted to share my thoughts on My Dema Dream, as I believe it might resonate with your skincare journey. From the moment I started using MyDerma Dream, I was impressed by it's lightweight formula. It glides on effortlessly and absorb quickly leaving my skin feeling refreshed and hydrated without any greasy feeling. This is especially important for someone like me who prefers alight touch in their skin care routine. After several weeks of consistent use, I've notice a remarkable difference in my skin. I wholeheartedly recommend MyDerma Dream to anyone looking to enhance their skincare routine. It's been a game-changer for me, and I believe it could be for you as well. Thank you MyDerma Dream.